MTB DNA PCR (BAL FLUID)
Also Known As
Test Parameters Included
- Mycobacterium tuberculosis DNA Detection (Qualitative) - PCR amplification of MTB-specific gene targets from BAL fluid
- Pathologist Molecular Microbiology Remark - correlated with clinical and radiological findings for pulmonary TB diagnosis
Department
Methodology
Sample Required
Preparation
Schedule Report
24 hours
Emergency Report
Yes
Frequently Asked Questions
What does MTB DNA PCR on BAL fluid detect?
It detects Mycobacterium tuberculosis genetic material in bronchoalveolar lavage fluid, enabling rapid diagnosis of pulmonary TB even when sputum smears are negative.
Why is BAL fluid used instead of sputum?
BAL fluid is collected when a patient cannot produce sputum spontaneously or when sputum tests are inconclusive. It provides a higher yield of organisms from the lower respiratory tract.
Is fasting required before this test?
No, fasting is not required. BAL fluid is obtained via bronchoscopy, and the procedure is performed by a pulmonologist based on clinical indication.
How long does the test take?
The PCR result is typically available within 24 hours from sample receipt at Dr. Patho Labs & Diagnostics.
What does a positive MTB PCR result mean?
A positive result indicates the presence of MTB DNA, suggesting active tuberculosis infection. However, it cannot distinguish between active disease and residual DNA from prior infection, so clinical correlation is essential.
Can antibiotics affect the PCR result?
PCR detects DNA and is not affected by prior antibiotic treatment, unlike culture. This makes it useful even after anti-TB therapy has been started.
Test Description
Test Code
M24
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