Test

Lupus Anticoagulant LA test - Na Citrate

₹3,375 ₹2,700

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Also Known As

No data available

Test Parameters Included

Lupus Anticoagulant Screening, Mixing, and Confirmation Results (ratio/normalised)
Pathologist Haematology Remark - interpreted against ISTH guidelines for antiphospholipid syndrome diagnosis

Department

HAEMATOLOGY

Methodology

Optical Clot Based

Sample Required

Na CITRATE - PLASMA (3ML)

Preparation

* Fasting is generally NOT required: Unless other tests are ordered simultaneously that require it. You can usually eat and drink as usual. * Medications - CRITICAL: This is paramount for LA testing: * Anticoagulants: If you are taking anticoagulant medications (e.g., Heparin, Warfarin/Coumadin, Direct Oral Anticoagulants like apixaban, rivaroxaban, dabigatran, edoxaban), they will interfere with the test results and can cause false positives or false negatives. * You MUST inform your doctor about all medications, especially anticoagulants. Your doctor will advise if you need to stop your anticoagulant therapy temporarily before the test (a "washout period") and for how long. NEVER stop prescribed medication without explicit instruction from your doctor. * Other medications (e.g., antiplatelet drugs like aspirin, clopidogrel) generally do not interfere. * Sample Collection: * Sodium Citrate Tube (Light Blue Top): The blood must be collected in this specific tube. * Correct Fill Volume: The tube must be filled to the indicated mark to ensure the correct blood-to-anticoagulant ratio (usually 9 parts blood to 1 part sodium citrate). Underfilling or overfilling can lead to inaccurate results. * Immediate Mixing: Gently invert the tube several times immediately after collection to ensure proper mixing with the anticoagulant. * Prompt Transport to Lab: The sample must be transported to the laboratory promptly for processing (centrifugation and plasma separation) and testing, usually within a few hours, to maintain the integrity of coagulation factors.

Schedule Report

24 Hours

Emergency Report

Yes

Frequently Asked Questions

What is a Lupus Anticoagulant test?

It is a specialised clotting test that detects lupus anticoagulant antibodies, which are autoantibodies targeting phospholipid-binding proteins. Despite the name, these antibodies are associated with clotting risk, not bleeding.

Why is citrate plasma required for this test?

Citrate plasma is used because it preserves coagulation factors accurately. Calcium is chelated during collection and must be carefully re-added during the assay to ensure precise clot-based measurements.

What conditions is this test used to diagnose?

Lupus anticoagulant testing is a key diagnostic criterion for antiphospholipid syndrome (APS), which causes recurrent thrombosis and pregnancy complications such as miscarriages. It may also be seen in autoimmune conditions like SLE.

How long does the test take?

The LA test involves screening, mixing, and confirmation steps across multiple coagulation platforms. Turnaround time is typically 24 to 48 hours at Dr. Patho Labs.

Does fasting affect Lupus Anticoagulant results?

No, fasting is not required for this test. However, certain medications like warfarin and direct oral anticoagulants can interfere with results, so inform your doctor before testing.

How is the report interpreted?

Results are reported as a normalised ratio from dilute Russell viper venom time (dRVVT) and silica clotting time (SCT). A prolonged screening ratio that fails to correct on mixing and is confirmed on the confirmatory step indicates a positive lupus anticoagulant.

Test Description

Lupus Anticoagulant LA Test - Na Citrate Examination Also Known As: LA Test, Lupus Anticoagulant Panel, aPL (antiphospholipid) functional assay The ...

Test Code

L19

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