Test

Liver Kidney Microsome LKM1 Antibody

₹3,000 ₹2,400
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Also Known As

No data available

Test Parameters Included

  • LKM1 Antibody Titer (Positive/Negative at reporting dilution) - semi-quantitative immunofluorescence or ELISA titer
  • Pathologist Immunology Remark - correlated with autoimmune hepatitis type 2 and drug-induced autoimmunity reference intervals
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Department

IMMUNOLOGY / SEROLOGY

Methodology

ELISA

Sample Required

SERUM (1ML)

Preparation

fasting is not required for the Liver-Kidney Microsomal (LKM) - 1 antibody test. This blood test can be performed at any time of the day.

Schedule Report

24 Hours

Emergency Report

Yes

Frequently Asked Questions

What does the LKM1 antibody test measure?

It detects autoantibodies directed against liver kidney microsome type 1 antigen (CYP2D6 enzyme), which is found in liver and kidney tissues. These antibodies are a key serological marker for autoimmune hepatitis type 2.

Is fasting required for this test?

No, fasting is not required for LKM1 antibody testing. The sample can be collected at any time of day without dietary restrictions.

What does a positive LKM1 antibody result indicate?

A positive result is strongly associated with autoimmune hepatitis type 2, which predominantly affects children and young adults. It may also be seen in autoimmune hepatitis type 3, primary biliary cholangitis, and certain drug-induced autoimmune conditions.

How are LKM1 antibody results reported?

Results are typically reported as positive or negative along with the antibody titer (e.g., 1:40, 1:160, 1:640). Higher titers generally correlate with greater disease activity and are more specific for autoimmune hepatitis type 2.

How is LKM1 different from ANA and SMA tests?

LKM1 targets the CYP2D6 enzyme in liver and kidney microsomes, while ANA targets nuclear components and SMA targets smooth muscle actin. Autoimmune hepatitis type 2 is LKM1-positive but ANA/SMA-negative, helping differentiate it from type 1 AIH.

How to access the report?

Verified PDF report is available within 24-48 hours via www.drpatholab.in or WhatsApp/Email after sample collection.

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Test Description

Liver Kidney Microsome LKM1 Antibody Examination What it measures The LKM-1 antibody test or liver kidney microsomal type 1 antibody test looks for t... Read more

Test Code

L21

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