Ionized Calcium
Also Known As
Test Parameters Included
- Serum Ionized Calcium Concentration (mg/dL or mmol/L) — free physiologically active calcium fraction
- Pathologist Clinical Biochemistry Remark — interpreted alongside total calcium, albumin, and ionized calcium reference intervals
Department
Methodology
Sample Required
Preparation
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
What is ionized calcium and how is it different from total calcium?
Ionized calcium is the free, unbound form of calcium in blood that is biologically active. Total calcium includes protein-bound and complexed calcium, so ionized calcium gives a more accurate picture of calcium status, especially in critically ill or hypoalbuminemic patients.
Is fasting required for ionized calcium test?
No, fasting is not required for this test. However, the sample must be collected in a heparinized tube and processed quickly to prevent CO2 loss, which can falsely elevate ionized calcium readings.
Why is ionized calcium more reliable in hospitalized patients?
Conditions like acid-base imbalance, low albumin, or critical illness alter calcium binding to proteins. Ionized calcium measurement bypasses these variables, giving a true reflection of available calcium for cellular function.
What conditions cause low ionized calcium?
Hypoparathyroidism, vitamin D deficiency, chronic kidney disease, magnesium deficiency, and severe illness with alkalosis can lower ionized calcium, leading to symptoms like muscle cramps, tingling, and seizures.
Can medications affect ionized calcium results?
Yes. Diuretics, antacids, bisphosphonates, calcium supplements, and blood transfusions containing citrate can alter ionized calcium levels. Always inform your doctor about current medications before testing.
How is the report delivered?
Verified PDF report is available within 24 hours via www.drpatholab.in or WhatsApp/Email after sample collection.
Test Description
Test Code
I12
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