HIV-1 Genotypic Drug Resistance - ( PI, RT ) - PCR Sequencing - EDTA PLASMA
Also Known As
Test Parameters Included
- HIV-1 Reverse Transcriptase (RT) and Protease (PI) Gene Mutation Profile (codon-level genotypic resistance)
- Pathologist Molecular Virology Remark - mapped against IAS-USA Stanford HIV Drug Resistance Mutations database for ART regimen guidance
Department
Methodology
Sample Required
Preparation
Schedule Report
15 Days
Emergency Report
Yes
Frequently Asked Questions
What does HIV-1 Genotypic Drug Resistance test measure?
It identifies specific genetic mutations in the HIV-1 reverse transcriptase and protease genes that confer resistance to antiretroviral drugs, guiding selection of effective ART regimens.
How is this different from a viral load (RNA) test?
Viral load measures the quantity of HIV RNA in blood, while genotypic resistance testing identifies which drug-resistant mutations are present. Both are complementary and often ordered together.
What sample is required for this test?
EDTA plasma is required. Whole blood in EDTA tube can also be used, and plasma is separated in the laboratory for PCR extraction.
When should this test be performed?
It is recommended at baseline before starting antiretroviral therapy, at treatment failure when virologic rebound occurs, and periodically as part of comprehensive HIV management.
How long does it take to get results?
Turnaround time is typically 5 to 7 working days, as PCR amplification and Sanger sequencing of RT and PI regions require careful laboratory processing.
Can I continue my current HIV medications during testing?
Yes, you should continue your antiretroviral medications as prescribed. The test detects existing resistance mutations regardless of whether you are currently on therapy.
Test Description
Test Code
H64
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