Factor - VIII Activity Assay
Also Known As
Test Parameters Included
- Factor VIII Coagulant Activity (%) - relative to normal pooled plasma reference
- Pathologist Haematology Remark - correlated with bleeding disorder reference intervals
Department
Methodology
Sample Required
Preparation
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
Is fasting required for Factor VIII Activity Assay?
No, fasting is not required. The test can be performed on a non-fasting sample.
What sample is collected for this test?
Citrated plasma (1 mL) is collected in a light blue top tube containing sodium citrate anticoagulant.
What does Factor VIII Activity Assay measure?
It measures the functional coagulant activity of Factor VIII, expressed as a percentage of normal pooled plasma, helping diagnose hemophilia A and von Willebrand disease.
How are results interpreted?
Normal range is typically 50–150%. Low activity indicates hemophilia A (mild: 5–40%, moderate: 1–5%, severe: <1%) or von Willebrand disease. Elevated levels may be seen in acute phase reactions, pregnancy, or liver disease.
Can medications affect Factor VIII levels?
Yes, oral contraceptives, hormone replacement therapy, and inflammatory states can raise Factor VIII levels. Anticoagulant therapy does not directly affect the assay but may require alternative testing.
How to access the report?
Verified PDF report is available within 24–48 hours via www.drpatholab.in or WhatsApp/Email.
Test Description
Test Code
F04
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