Endomysial Antibody IgM
Also Known As
Test Parameters Included
- Serum Endomysial Antibody IgM Concentration (IU/mL) - indirect immunofluorescence or ELISA quantification
- Pathologist Immunology Remark - correlated against celiac disease reference intervals
Department
Methodology
Sample Required
Preparation
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
What does Endomysial Antibody IgM test measure?
It detects IgM autoantibodies directed against the endomysium, the connective tissue surrounding smooth muscle fibers in the small intestine. These antibodies are highly specific markers for celiac disease.
Is fasting required for this test?
No, fasting is not required for Endomysial Antibody IgM testing. The sample can be collected at any time of day without dietary restrictions.
What do positive results indicate?
A positive EMA IgM result strongly suggests celiac disease, as this antibody has high specificity (over 95%) for the condition. Further evaluation with tTG-IgA and possibly duodenal biopsy is recommended for confirmation.
How is the sample collected?
A standard venous blood draw of approximately 1 mL of serum is collected in a plain or clot-activator tube. The sample is then processed and tested using ELISA or indirect immunofluorescence methodology.
Can EMA IgM be negative in celiac disease?
Yes, especially in IgA-deficient patients or early-stage disease. IgA deficiency is more common in celiac patients, so IgG-based tests may be needed as a complementary screening approach.
How to access the report?
Verified PDF reports are available within 24–48 hours via www.drpatholab.in or through WhatsApp/Email from Dr. Patho Labs & Diagnostics, Chhatrapati Sambhajinagar.
Test Description
Test Code
E02
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