Desmoglein III Antibody
Also Known As
Test Parameters Included
- Serum Desmoglein III Antibody Concentration (IU/mL)
- Pathologist Immunology Remark – correlated with pemphigus vulgaris disease activity and mucosal involvement
Department
Methodology
Sample Required
Preparation
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
Is fasting required for Desmoglein III Antibody test?
No, fasting is not required. The test measures autoantibodies and is unaffected by recent food intake.
What sample is collected and how much?
A 3 mL serum sample is collected via venipuncture. The blood is allowed to clot and then centrifuged to separate the serum for ELISA testing.
How long does it take to get the report?
Reports are typically available within 2–3 working days from sample receipt at Dr. Patho Labs, Chhatrapati Sambhajinagar.
What do positive results indicate?
Positive Desmoglein III antibodies are strongly associated with pemphigus vulgaris, particularly the mucosal-dominant form. Higher titers often correlate with active disease and may guide immunosuppressive therapy adjustments.
Can medications affect the test result?
Immunosuppressive drugs like corticosteroids or rituximab may lower antibody titers over time. Inform your doctor about all current medications for accurate interpretation.
Is this test used for monitoring treatment response?
Yes, serial quantitative testing helps monitor disease activity and treatment efficacy. Falling titers usually indicate clinical improvement in pemphigus vulgaris.
Test Description
Test Code
D25
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