Desmoglein I Antibody
Also Known As
Test Parameters Included
- Serum Anti-Desmoglein I (Dsg1) Antibody Concentration (IU/mL) by ELISA
- Pathologist Immunology Remark - correlated with pemphigus subtyping and disease activity
Department
Methodology
Sample Required
Preparation
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
What is Desmoglein I Antibody test used for?
It detects autoantibodies against Desmoglein-1, a protein in skin cell junctions. Elevated levels help diagnose pemphigus foliaceus and some cases of pemphigus vulgaris.
Is fasting required for this test?
No, fasting is not required. Serum sample can be collected at any time of day.
What do positive Dsg1 antibody results mean?
Positive results indicate an autoimmune attack on superficial skin layers, commonly seen in pemphigus foliaceus. Levels often correlate with disease activity and can be monitored over time.
How is the sample collected?
A standard venous blood draw of approximately 3 mL into a plain serum tube is collected and processed by ELISA methodology.
Can this test distinguish between pemphigus types?
Dsg1 antibodies are typically positive in pemphigus foliaceus and may be positive in mucocutaneous pemphigus vulgaris. Dsg3 antibody testing is usually done alongside for accurate subtyping.
How to access the report?
Verified PDF report is available within 48–72 hours via www.drpatholab.in or WhatsApp/Email.
Test Description
Test Code
D24
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