Cotinine Urine ( Nicotine metabolite )
Also Known As
Test Parameters Included
- #1) Urine Cotinine Concentration:
This measures the specific amount of cotinine in the urine. The concentration level helps distinguish between active smokers, users of nicotine replacement therapy (NRT), and those exposed to significant secondhand smoke.
Department
Methodology
Sample Required
Preparation
Schedule Report
2 Days
Emergency Report
Yes
Frequently Asked Questions
How long does cotinine stay in urine?
It typically remains detectable for 3 to 4 days after the last use of nicotine. In heavy users, it may be detectable for up to a week.
Why does the report take 2 days?
While the initial screen is fast, the lab ensures all samples are properly handled, processed, and verified to prevent "false positives".
Will "vaping" cause a positive result?
Yes. E-cigarettes still contain nicotine, which your body metabolizes into cotinine.
Can secondhand smoke make me fail the test?
Highly sensitive tests can detect passive exposure, but most labs use a "cut-off" level designed to distinguish between active smokers and passive breathers.
Does nicotine gum show up?
Yes, all forms of nicotine replacement therapy (NRT) will produce a positive cotinine result.
Why use Cotinine instead of Nicotine for the test?
Nicotine disappears from the body in hours, whereas cotinine is much more stable and stays in the system much longer.
What is the "Tube Method" of collection?
For this test, you simply provide a mid-stream urine sample in a sterile container provided by the lab.
Can I drink water before the test?
Yes, but avoid "over-hydrating" (drinking excessive amounts), as very dilute urine can sometimes lower the concentration of cotinine below the detection limit.
Are there any medications that interfere?
Generally, no. Standard medications do not usually cause cross-reactivity with cotinine antibodies in immunochromatography.
Does a negative result mean I've never smoked?
No, it only means you haven't used nicotine in the roughly 72 to 96 hours before the test.
Why is 10ml of urine needed?
This volume ensures there is enough sample for the initial screen and any necessary repeat testing for accuracy.
Is this test used for legal purposes?
Yes, it can be used in child custody cases or for insurance fraud investigations where smoking status is a factor.
Does age affect the result?
Metabolism speeds vary by age, but the 3-to-4-day detection window remains the standard for most adults.
What are "Alkaloid Metabolites"?
This is the scientific category for molecules like cotinine that come from natural plant compounds like nicotine.
Is the test result confidential?
Absolutely. At Dr. Patho, all substance-related testing is handled with the highest level of privacy and data protection.
Test Description
Test Code
N01
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