Calprotectin - Stool
Also Known As
Test Parameters Included
- Fecal Calprotectin Concentration (μg/g) - quantitative neutrophil-derived protein marker
- Pathologist Gastroenterology Remark - interpreted against IBD vs functional bowel reference intervals
Department
Methodology
The test is performed using the Immunochromatography method, often referred to as a rapid test. This technique is based on a simple principle:
* Antigen-Antibody Reaction: The stool sample is processed to extract calprotectin (the antigen). This is then allowed to move along a test strip.
* Detection: The strip contains immobilized antibodies specific to calprotectin. If calprotectin is present in the sample, it binds to these antibodies, producing a visible colored line or signal. The intensity of this signal can be measured to provide a quantitative or semi-quantitative result.
This method is known for its speed, ease of use, and reliability in a clinical laboratory setting.
Sample Required
Preparation
#2) Fresh Sample: The stool sample should be collected as a fresh sample. It is best to collect the sample in the morning and transport it to the lab as soon as possible.
#3) Avoid Contamination: Ensure the sample is not contaminated with urine or toilet water. The stool should be collected from a clean, dry surface.
#4) Sample Size: Only a small, pea-sized portion is required. Follow the instructions on the collection container.
#5) No Special Diet: There are no specific dietary restrictions required before this test.
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
What does stool calprotectin test measure?
Fecal calprotectin is a protein released by neutrophils during intestinal inflammation. It helps distinguish inflammatory bowel disease (IBD) from functional disorders like IBS.
Is fasting required for this test?
No, fasting is not required. Stool sample can be collected at any time of day without dietary restrictions.
How is the stool sample collected?
A small, pea-sized portion of freshly passed stool is collected in the sterile container provided by the lab. Avoid contamination with urine or toilet water.
What do high calprotectin levels indicate?
Elevated levels suggest active intestinal inflammation, commonly seen in Crohn's disease and ulcerative colitis. Levels help monitor disease activity and response to treatment.
Can medications affect calprotectin results?
NSAIDs and some anti-inflammatory drugs may mildly elevate calprotectin. Inform your doctor about all medications before testing.
What is the turnaround time for results?
Results are typically available within 24–48 hours. Verified reports can be accessed via www.drpatholab.in or WhatsApp/Email.
Test Description
Test Code
C98
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