APLA Anti Phospholipid Screen IgG, IgM Combined
Also Known As
Test Parameters Included
- Anti-Phospholipid Antibody IgG Concentration (IU/mL) - quantitative IgG class antibody detection
- Anti-Phospholipid Antibody IgM Concentration (IU/mL) - quantitative IgM class antibody detection
- Pathologist Immunology Remark - correlated with clinical criteria for antiphospholipid syndrome
Department
Methodology
Sample Required
Preparation
Schedule Report
24 hours
Emergency Report
Yes
Frequently Asked Questions
What does the APLA IgG IgM Combined test detect?
It detects IgG and IgM antibodies directed against phospholipid-binding proteins such as beta-2 glycoprotein I and cardiolipin. These antibodies are the hallmark serological markers of antiphospholipid syndrome (APS).
Why are both IgG and IgM measured together?
Measuring both classes increases diagnostic sensitivity. Some patients produce only IgG, others only IgM, and a subset produces both. Combined testing reduces the chance of missing APS.
Is fasting required for this test?
No, fasting is not required. Anti-phospholipid antibodies are not affected by recent food intake, so the sample can be collected at any time of day.
How is the result interpreted?
Positive results indicate the presence of antiphospholipid antibodies. Diagnosis of APS requires at least one positive test on two separate occasions at least 12 weeks apart, along with clinical criteria such as thrombosis or pregnancy morbidity.
Can this test be positive in other conditions?
Yes. Transient positive results can occur with infections, autoimmune diseases like SLE, certain medications, and in healthy elderly individuals. Clinical correlation and repeat testing are essential before diagnosing APS.
How to access the report?
Verified PDF report is available within 24–48 hours via www.drpatholab.in or through WhatsApp and email notification.
Test Description
Test Code
PP5
- High-end laboratory & medical equipment.
- Outstanding doctor team.
- Personalized care & high-quality service.
- Tailormade health screening packages.