Adenosine Deaminase (ADA) CSF
Also Known As
Test Parameters Included
- CSF Adenosine Deaminase (ADA) Enzyme Activity measured in (U/L)
- Pathologist Clinical Biochemistry Remark — interpreted against tuberculous meningitis reference thresholds
Department
Methodology
Sample Required
Preparation
Schedule Report
24 Hours
Emergency Report
Yes
Frequently Asked Questions
What does the CSF ADA test measure?
It measures the activity of adenosine deaminase enzyme in cerebrospinal fluid, serving as a key biochemical marker for diagnosing tuberculous meningitis.
Why is ADA elevated in tuberculous meningitis?
In TB meningitis, activated lymphocytes and macrophages release high amounts of ADA enzyme into the CSF, making it a sensitive and specific indicator of mycobacterial infection in the meninges.
What is the normal range for CSF ADA?
Normal CSF ADA levels are typically below 8–10 U/L. Values above this cutoff strongly suggest tuberculous meningitis, though the exact threshold may vary by laboratory methodology.
Is this test performed on blood or CSF?
This test requires a CSF sample obtained through lumbar puncture, not a blood sample.
How quickly are results available?
Results are typically available within 24 hours at our NABL-accredited laboratory in Chhatrapati Sambhajinagar.
Can other conditions raise CSF ADA levels?
Yes, bacterial meningitis, fungal infections, and certain CNS malignancies can also elevate ADA, so results must always be interpreted alongside clinical presentation and other investigations such as CSF culture and PCR.
Test Description
Test Code
A14
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