Test

iPTH Intact Parathyroid Hormone / Parathormone / PTH (1-84)

₹1,600 ₹1,400
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Also Known As

#1) Intact PTH (1-84) Assay #2) Quantitative Bio-Intact Parathormone Screen #3) Core Calcium-Phosphorus Axis Panel #4) Chemiluminescent Intact PTH Triage #5) Primary Hyperparathyroidism Marker #6) Kinetic Serum iPTH Profile #7) High-Sensitivity Renal Osteodystrophy Audit #8) Targeted Serum Polypeptide Study #9) Calciotropic Endocrine Tracking Index #10) Microvascular Parathyroid Secretory Index #11) Post-Operative Parathyroid Baseline #12) Executive Bone Mineral Clearance Profile #13) PathoFit Advanced Mineral Oncology Package #14) Absolute Circulating iPTH Mass Load #15) Standard Serological CLIA iPTH Protocol
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Test Parameters Included

  • Serum Intact Parathyroid Hormone (iPTH) Concentration Level: The direct quantitative measurement of the active, complete 1-84 amino acid parathormone chain circulating in the blood fluid, standardly reported in picograms per milliliter (pg/mL).
  • Pathologist Clinical Endocrinology Remark: A comprehensive medical evaluation mapping your exact non-fragmented hormone score against concurrent mineral baselines to evaluate hyper-functional or suppressed glandular pathways.
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Department

CLINICAL BIOCHEMISTRY

Methodology

Chemiluminescence : The serum sample is processed using a fully automated **Chemiluminescence Immunoassay (CLIA)** platform. In short, this advanced method mixes your clear centrifuged blood serum with magnetic microparticles coated with targeted anti-iPTH antibodies, followed by a secondary antibody tagged with a light-emitting chemical marker to form an immunological "sandwich." Specialized trigger solutions are then introduced to initiate a rapid reaction that causes the marker to emit a sharp burst of light. Because the absolute intensity of the emitted light photons scales mathematically with the exact weight of the proteins captured, an ultra-precise optical luminometer can accurately count trace molecular shifts while entirely removing human visual error.
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Sample Required

SERUM (1ML)

Preparation

* **No Fasting Required:** You can eat and drink normally before your sample collection. * **The Diurnal Timing Note:** **Your blood sample should standardly be drawn during early morning laboratory operating hours (typically between 8:00 AM and 10:00 AM).** iPTH levels naturally exhibit a cyclic peak during the early morning hours; collecting your sample during this standardized window ensures an accurate, stable baseline comparison. * **The Biotin Safeguard:** Pause high-dose Biotin supplements for at least 48 hours prior to testing, as heavy doses of biotin can interfere with the binding hooks inside automated CLIA analyzers. * **Sample Type:** Requires a standard venous blood sample (Serum) collected in a standard red-top or gold-top gel-barrier clot-activator tube.
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Schedule Report

12 Hours

Emergency Report

Yes

Frequently Asked Questions

Why does the Serum iPTH test report require a 6-hour turnaround window?

While the automated chemical analysis runs rapidly inside the instrument, delivering a high-precision endocrine result requires standard sample clotting, high-speed centrifugation to isolate clear serum, precise multi-point machine calibrations, and final validation by our pathodiagnostic team to ensure absolute accuracy.

What exactly is an "Intact" PTH test compared to older hormone checks?

Older hormone checks counted both the active hormone and broken, inactive hormone fragments that naturally float in the blood, leading to mixed readings. The modern "Intact" assay uses specific antibody pairs that bind only onto the complete, undamaged 1-84 amino acid chain, capturing your true live hormone activity.

Why is it standard practice to draw this blood sample strictly in the morning?

Your body releases parathyroid hormone following a natural daily pattern, with levels rising steadily through the night to reach a peak in the early morning hours. Standardizing your collection between 8:00 AM and 10:00 AM ensures your results can be accurately compared against baseline reference values.

How do the parathyroid glands differ from the thyroid gland?

Though they sit right next to each other in the neck and share part of a name, they belong to entirely separate organ systems. The thyroid gland controls your body's overall metabolism and energy pace. The four tiny parathyroid glands act strictly as a mineral thermostat to regulate blood calcium and phosphorus levels.

Why do doctors need to view my blood calcium level at the exact same time as my iPTH score?

iPTH and calcium exist in a continuous feedback loop. A high iPTH score is completely normal if your blood calcium is low, as it shows the glands are working properly to fix a deficit. However, a high iPTH paired with a high calcium level confirms a communication breakdown, helping doctors identify the root cause of the issue.

Do I need to be completely fasting for 10–12 hours before providing this blood draw?

No, fasting is entirely unnecessary for a standalone serological iPTH panel. Your sample can be safely and comfortably collected at whichever hour of the day fits your scheduled morning window best.

What exactly is a parathyroid adenoma?

A parathyroid adenoma is a completely benign, non-cancerous growth that develops on one of your four parathyroid glands. Even though it is non-cancerous, it causes health issues by ignoring your body's feedback loops and continuously pumping excess hormones into your bloodstream.

Can severe chronic kidney disease cause my parathyroid hormone levels to rise?

Yes, heavily. When kidney filtration slows down, the kidneys lose their capacity to clear phosphorus from the blood and fail to activate Vitamin D. This imbalance drops your circulating calcium levels, forcing your healthy parathyroid glands to work overtime and causing secondary hyperparathyroidism.

Why does taking high-dose Biotin vitamins matter for my iPTH report sheet?

High doses of biotin found in hair and nail formulas can interfere with the chemical binding hooks used inside automated chemiluminescence machinery. This can warp your true numbers under the lamp, which is why you should pause these supplements for 48 hours before testing.

What are the common symptoms experienced if my parathyroid hormone levels are too high?

Chronic overproduction can leach calcium from your skeleton, leading to a classic set of symptoms described as "stones, bones, abdominal groans, and psychic moans"—which translates to painful kidney stones, deep bone aches, severe constipation, muscle weakness, and mild confusion.

What happens if all four parathyroid glands are accidentally damaged during neck surgery?

If the glands are bruised or removed during extensive thyroid surgery, your iPTH levels will drop down to near-zero (hypoparathyroidism). This stops your body's calcium-recruiting pathways, causing a rapid drop in blood calcium that presents as tingling around the mouth and painful muscle cramps.

Can a severe, long-standing Vitamin D deficiency alter my iPTH baseline?

Yes. Vitamin D is required for your digestive tract to absorb calcium from your meals. If your Vitamin D stores drop, calcium absorption fails. Your parathyroid glands detect this drop and release high levels of iPTH to pull calcium from your bones instead, balancing the blood at the expense of your skeleton.

What is "Renal Osteodystrophy" noted in advanced laboratory medicine discussions?

Renal Osteodystrophy is a bone-weakening disease that develops in patients managing long-standing kidney decline. It occurs when chronic secondary hyperparathyroidism continuously leaches structural minerals from the skeleton, leaving the bones brittle and vulnerable to fractures.

Can a person have an elevated iPTH score if their parathyroid glands are completely normal?

Yes. In secondary hyperparathyroidism, the glands themselves are healthy. They are simply responding properly to an outside issue, such as poor kidney clearing or a severe lack of Vitamin D, by ramping up production to protect blood calcium levels.

Why is Chemiluminescence (CLIA) preferred over old manual testing methods?

Older manual tests required visual matching and could easily miss trace protein shifts. Modern automated CLIA technology utilizes precise optical photon sensors to count actual bursts of chemical light, ensuring world-class quantitative consistency down to exact micro-fractions.

Is this endocrine monitoring panel safe and standard for individuals tracking bone health?

Yes, highly vital. It requires a simple, non-invasive blood draw from an arm vein that carries zero risk, making it an exceptional tool for safe, long-term monitoring throughout your health journey.

Can a common seasonal cold or a viral fever cause my parathyroid hormone to spike?

A standard short-term cold virus will not alter your mineral-regulating pathways or cross-react with the highly specific antibodies used inside our testing channels, keeping your endocrine baseline completely clear.

What is the standard medical care if a primary parathyroid growth is confirmed?

The definitive treatment for a primary adenoma is the surgical removal of the affected tiny gland, a minor procedure called a parathyroidectomy. Once the single overactive growth is removed, your remaining healthy glands quickly take over and restore normal mineral balance.

How can I securely access and download my final 6-hour digital PDF report?

As soon as your biochemical hormone profile is thoroughly verified, authorized, and signed off by our laboratory pathology team, your secure digital report can be downloaded instantly from www.drpatholab.in using your registered credentials.

Are my personal endocrine records, bone mineral profiles, and lab screening histories kept private?

Absolutely. We maintain strict medical privacy standards, secure patient confidentiality safeguards, and fully encrypted data channels across our entire digital infrastructure to guarantee your entire diagnostic profile remains completely private and secure.

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Test Description

Serum Intact Parathyroid Hormone (iPTH / PTH 1-84) The Serum Intact Parathyroid Hormone (iPTH) test is a high-sensitivity endocrine assay utilized as ... Read more

Test Code

I09

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