Soluble Transferrin Receptor Serum
Also Known As
Test Parameters Included
- Soluble Transferrin Receptor (sTfR) Concentration (mg/L) - reflects erythropoietic activity and cellular iron demand
- Pathologist Hematology Biochemistry Remark - interpreted alongside iron studies and hemoglobin to differentiate iron deficiency from anemia of chronic disease
Department
Methodology
Sample Required
Preparation
Schedule Report
72 Hours
Emergency Report
Yes
Frequently Asked Questions
What does soluble transferrin receptor measure?
sTfR reflects the number of transferrin receptors on red blood cell precursors, indicating how much iron cells are trying to uptake. Elevated levels signal increased erythropoietic demand, most commonly due to iron deficiency.
How is sTfR different from ferritin?
Ferritin measures iron stores but rises during inflammation as an acute-phase reactant, giving false-normal results. sTfR is not influenced by inflammation, making it a more reliable indicator of true iron deficiency in patients with chronic disease.
When is this test ordered?
It is used when iron deficiency anemia is suspected but ferritin results are inconclusive, particularly in patients with chronic inflammation, kidney disease, or liver disorders where ferritin may be falsely elevated.
Is fasting required for sTfR testing?
No, fasting is not required. The test can be performed on a non-fasting serum sample at any time of day.
What do high sTfR levels indicate?
Elevated sTfR indicates increased red blood cell production driven by iron deficiency, hemolytic anemias, or ineffective erythropoiesis. It helps confirm iron deficiency even when ferritin appears normal due to underlying inflammation.
How is the result interpreted?
Results are interpreted alongside CBC, serum ferritin, TIBC, and serum iron. An elevated sTfR with low ferritin confirms iron deficiency anemia, while elevated sTfR with normal-high ferritin suggests anemia of chronic disease with coexisting iron deficiency.
How to access the report?
Verified PDF report is available within 24 hours via www.drpatholab.in or through WhatsApp/Email from Dr. Patho Labs & Diagnostics, Chhatrapati Sambhajinagar.
Test Description
Test Code
STOO1
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