Test

TORCH Profile 10 - IgG & IgM / Congenital Infection Screen

₹4,250 ₹2,299
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Also Known As

#1) Comprehensive 10-Parameter TORCH Panel #2) Congenital Infection Antibody Screen #3) Maternal-Fetal Infectious Disease Baseline #4) Quantitative ELISA TORCH Profile 10 #5) Prenatal TORCH Triage Panel #6) Perinatal Pathogen Immunity Audit #7) Complete IgG and IgM TORCH Study #8) Targeted Fetotoxic Pathogen Screen #9) Gestational Immunity & Exposure Baseline #10) Microvascular TORCH Antibody Index #11) Acute-Chronic Congenital Screen Array #12) Executive Prenatal Infection Screen #13) PathoFit Advanced TORCH 10 Package #14) Absolute Circulating TORCH Antibody Load #15) Standard 10-Test TORCH Protocol
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Test Parameters Included

  • Toxoplasma gondii (Toxo) IgG: Indicates past exposure and immunity.
  • Toxoplasma gondii (Toxo) IgM: Indicates recent or acute infection.
  • Rubella IgG: Indicates past exposure and immunity.
  • Rubella IgM: Indicates recent or acute infection.
  • Cytomegalovirus (CMV) IgG: Indicates past exposure and immunity.
  • Cytomegalovirus (CMV) IgM: Indicates recent or acute infection.
  • Herpes Simplex Virus (HSV) 1 IgG: Indicates past exposure and immunity to HSV Type 1.
  • Herpes Simplex Virus (HSV) 1 IgM: Indicates recent or acute HSV Type 1 infection (interpret cautiously).
  • Herpes Simplex Virus (HSV) 2 IgG: Indicates past exposure and immunity to HSV Type 2.
  • Herpes Simplex Virus (HSV) 2 IgM: Indicates recent or acute HSV Type 2 infection (interpret cautiously).
  • INCLUDED TEST PARAMETERS & IMMUNE ARCHITECTURE (10 TESTS):
  • This profile systematically pairs IgG (Immunoglobulin G) and IgM (Immunoglobulin M) antibodies for each pathogen. IgM is the first antibody your immune system builds to fight a brand-new infection, serving as a marker for a fresh, acute phase. IgG develops slightly later, peaking after a few weeks, and remains in your bloodstream for months, years, or even a lifetime, serving as a permanent record of past exposure and baseline immunity.
  • Toxoplasma gondii (Toxo) Tracks (2 Tests)
  • Toxoplasma gondii IgG: Confirms historical exposure or long-term baseline immunity to this parasite.
  • Toxoplasma gondii IgM: Identifies a fresh, recent, or acute infection. Toxoplasma is a protozoan parasite typically contracted through undercooked meat, unwashed produce, or accidental exposure to infected cat feces.
  • Rubella Virus (German Measles) Tracks (2 Tests)
  • Rubella IgG: Verifies long-term protective immunity, typically acquired through past childhood infection or formal vaccination lines.
  • Rubella IgM: Indicates a recent, acute infection with the Rubella virus, which can cause severe congenital anomalies if contracted in the first trimester.
  • Cytomegalovirus (CMV) Tracks (2 Tests)
  • Cytomegalovirus IgG: Indicates a past exposure or a latent, resting CMV infection.
  • Cytomegalovirus IgM: Indicates an acute, fresh primary infection or a sudden reactivation of this extremely common member of the herpesvirus family.
  • Herpes Simplex Virus Type 1 (HSV-1) Tracks (2 Tests)
  • HSV-1 IgG: Shows historical exposure or a latent infection with HSV-1, the virus primarily responsible for standard oral cold sores, though it can also cause genital lesions.
  • HSV-1 IgM: Points to a recent or acute primary outbreak of HSV-1. Must be interpreted cautiously alongside physical signs.
  • Herpes Simplex Virus Type 2 (HSV-2) Tracks (2 Tests)
  • HSV-2 IgG: Confirms historical exposure or a latent infection with HSV-2, the leading cause of sexually transmitted genital herpes outbreaks.
  • HSV-2 IgM: Suggests an acute primary outbreak or a sharp, symptomatic flare-up of the HSV-2 virus. Must be interpreted cautiously alongside physical signs.
  • TEST PREPARATION:
  • No Fasting Required: You can eat and drink normally before your blood collection.
  • Timing: The blood sample can be drawn safely at any hour of the day or night during operating hours.
  • Clinical Note: Always inform the laboratory technician if you are currently taking immunosuppressive drugs, or if you have recently received any live-attenuated vaccines (like the MMR vaccine), as these can directly influence your circulating antibody counts.
  • Sample Required: A standard venous blood sample (Serum) collected in a clot-activator tube.
  • SYMPTOMS / CLINICAL INDICATIONS:
  • Preconception & Early Prenatal Screening: Standardly recommended for women who are planning a pregnancy or during their very first prenatal doctor visit to check their baseline immunity profile and rule out active, silent infections.
  • Investigation of Complications: Evaluated during pregnancy if a woman experiences unexpected gestational complications or unexplained flu-like symptoms.
  • Physical Fluctuations in Pregnancy: Unexplained low-grade fevers, swollen lymph nodes in the neck or groin, or localized rashes.
  • Newborn Evaluations: Ordered for infants displaying signs of potential congenital exposure right after birth, such as a low birth weight, unexplained jaundice, small purplish skin spots (petechiae), or developmental delays.
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Department

IMMUNOLOGY / SEROLOGY

Methodology

ELISA : The serum sample is processed using an automated **ELISA (Enzyme-Linked Immunosorbent Assay)** platform. Inside the analyzer, your serum is introduced into ten parallel rows of plastic microwells, each pre-coated with purified antigens matching the specific TORCH targets. If your blood contains the corresponding IgG or IgM antibodies, they bind tightly onto these target catchments. Following an ultra-precise washing cycle to flush out unrelated blood proteins, specialized enzyme-linked antibody conjugates are added to lock the target molecules into an immunological complex. Finally, a color-triggering substrate is injected, generating a distinct color shift inside the well. The spectrophotometer shoots a highly calibrated light wavelength through the liquid to scan the precise depth of the color. Because the color intensity scales mathematically with the volume of target antibodies circulating in your blood fluid, ELISA delivers exceptional precision, entirely removing human reading bias.
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Sample Required

SERUM (2ML)

Preparation

* **No Fasting Required:** You can eat and drink normally before your blood collection. * **Timing:** The blood sample can be drawn safely at any hour of the day or night during operating hours. * **Clinical Note:** Always inform the laboratory technician if you are currently taking immunosuppressive drugs, or if you have recently received any live-attenuated vaccines (like the MMR vaccine), as these can directly influence your circulating antibody counts. * **Sample Required:** A standard venous blood sample (Serum) collected in a clot-activator tube.
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Schedule Report

24 hours

Emergency Report

Yes

Frequently Asked Questions

Why does the TORCH Profile 10 require a 24-hour turnaround?

Processing 10 distinct, simultaneous IgG and IgM parameters via automated ELISA requires extensive multi-stage incubation blocks, precise fluidic well washing steps to clear baseline serum variables, optical color development runs, and a final thorough validation loop by our senior laboratory pathologist to ensure total diagnostic precision.

What does "interpret cautiously" mean next to the HSV IgM parameters?

HSV-1 and HSV-2 share a nearly identical genetic architecture. Because their structures are so similar, early-stage IgM antibodies can occasionally cross-react on an ELISA tray, meaning a positive HSV-1 IgM could actually be triggered by an active HSV-2 outbreak, or vice-versa. Pathologists recommend checking long-term IgG typing and direct blister PCR swabs to confirm the exact strain.

If my Rubella IgG line is strongly positive but my IgM is negative, what does it mean?

This is an excellent, protective finding. It proves that you possess long-term, stable immunity against the Rubella virus, either from a childhood vaccination (like the MMR vaccine) or a past resolved exposure. You are safely protected against catching a primary Rubella infection during pregnancy.

Can I safely take this 10-test panel while actively menstruating?

Yes, absolutely. Hormonal shifts or active menstrual bleeding will not alter the structural immunoglobulins (antibodies) circulating in your bloodstream, meaning you can have your sample drawn at any point in your monthly cycle.

Do I need to be fasting before coming into the laboratory for this blood draw?

No, fasting is completely unnecessary for a standalone serological ELISA panel. Your blood sample can be collected comfortably at whichever hour of the day or night fits your schedule best.

How does a person contract Toxoplasmosis?

Toxoplasma gondii is a parasite commonly found in contaminated soil, undercooked or raw meats, unwashed fruits and vegetables, or through accidental contact with infected cat feces (such as while cleaning a litter box).

Why is a brand-new CMV infection dangerous during pregnancy if it feels like a normal cold to me?

In healthy adults, Cytomegalovirus (CMV) usually causes no symptoms or a mild sore throat. However, if a pregnant woman catches it for the very first time, the live virus can pass through the placenta and cause Congenital CMV, which can lead to hearing loss, vision changes, or developmental delays for the infant after birth.

Can a positive IgM result be a mistake or a false positive?

Yes, it can occasionally occur due to background variables. Certain active viral strains, background autoantibodies (like Rheumatoid Factor), or generalized immune flares can sometimes cause a low-grade, cross-reactive positive mark on an IgM well. Pathologists always look at your IgG scores and physical symptoms to cross-verify the staging.

What is the biological "window period" for a TORCH panel?

The window period is the time it takes your immune system to manufacture enough measurable antibodies following an initial exposure. For most TORCH pathogens, early-response IgM antibodies cross the laboratory's automated detection thresholds within 1 to 2 weeks after exposure.

If my results show I am negative for all 10 parameters, what should I do?

Testing completely negative means you have no active infection, but it also means you carry no protective immunity against these pathogens. If you are pregnant or planning a pregnancy, you should practice careful preventative hygiene: wash produce thoroughly, avoid raw foods, have someone else clean cat litter boxes, and practice safe hand hygiene.

Why is the ELISA methodology preferred over simple rapid test strips?

ELISA utilizes highly sensitive, enzyme-linked chemical coloring targets read by fully calibrated optical software. This automated process completely removes human reading bias and human error, providing exceptionally stable quantitative index ratios down to trace micro-fractions.

If I have been treated for Chlamydia or Gonorrhea in the past, will it alter my TORCH profile?

No. TORCH screens look for highly specific, individual antibodies engineered strictly to target Toxoplasma, Rubella, CMV, and Herpes viruses, completely avoiding cross-reactivity with unrelated bacterial STIs.

Is this 10-parameter package safe for young children or newborns?

Yes, absolutely. For pediatric or newborn cases where congenital tracking is requested, we use specialized ultra-fine needles and dedicated collection protocols to ensure a safe, quick, and comfortable draw.

How can I securely access and download my final 24-hour PDF report?

Once thoroughly verified and authorized by our laboratory pathodiagnostic team, your secure integrated PDF report can be instantly downloaded from www.drpatholab.in using your registered credentials.

Are my personal prenatal, family planning, and infectious disease records kept secure?

Absolutely. We enforce strict medical privacy regulations, patient confidentiality safeguards, and fully encrypted data tracks across our entire digital infrastructure to ensure your diagnostic profile remains completely private and secure.

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Test Description

TORCH Profile 10 - IgG & IgM / Congenital Infection Screen Examination The TORCH Profile 10 is an essential, multi-parameter serological screenin... Read more

Test Code

PT10

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