New Born Screening NBS - 111 Conditions On GCMS
Test Code
MOG36
Also Known As
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Test Parameters Included
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Department
MOLECULAR GENETICS
Methodology
GCMS (Gas Chromatography-Mass Spectrometry)
GCMS (Gas Chromatography-Mass Spectrometry) is the primary and highly specialized methodology for this specific newborn screening panel. GCMS is a powerful analytical technique that combines two different methods to identify and quantify specific substances within a complex sample, such as urine.
* Gas Chromatography (GC): Separates volatile and semi-volatile compounds in the sample based on their different chemical and physical properties (e.g., boiling point, polarity) as they pass through a capillary column.
* Mass Spectrometry (MS): Identifies the separated compounds by measuring their mass-to-charge ratio. Each compound has a unique "fingerprint" spectrum.
In the context of newborn screening for metabolic disorders, GCMS is particularly effective for detecting Organic Acidemias (Organic Acidurias). These are a group of inborn errors of metabolism where the body cannot properly break down certain amino acids, fats, or carbohydrates, leading to a buildup of toxic organic acids in the blood and urine. GCMS provides a detailed metabolic profile, identifying the specific organic acids that accumulate, which is crucial for diagnosing these conditions.
Sample Required
URINE: (A urine sample is the required specimen for this specific GCMS-based newborn screening panel.)
Preparation
Preparation for this urine-based newborn screening test is crucial for accurate results. * Sample Type: Only a urine sample is required for this specific panel. It is often collected in conjunction wi... Read more
Schedule Report
7 Days
Emergency Report
Yes
Frequently Asked Questions
No data available
Test Description
- High-end laboratory & medical equipment.
- Outstanding doctor team.
- Personalized care & high-quality service.
- Tailormade health screening packages.