Molecular Genetic TPMT Genotype - RT-PCR
Test Code
MOG10
Also Known As
No data available
Test Parameters Included
No data available
Department
MOLECULAR GENETICS
Methodology
RT-PCR (Reverse Transcription Polymerase Chain Reaction) / PCR / Allele-Specific PCR / Real-time PCR
The Molecular Genetic TPMT Genotype test primarily utilizes PCR (Polymerase Chain Reaction), often in the form of Allele-Specific PCR or Real-time PCR, for detecting specific genetic variations (polymorphisms) within the TPMT gene. While the prompt mentions RT-PCR, this test directly analyzes DNA, not RNA, to determine the genotype. PCR-based methods are highly sensitive and specific for identifying key single nucleotide polymorphisms (SNPs) within the TPMT gene. These SNPs are associated with altered enzyme activity. By amplifying and detecting these specific variants, the test determines an individual's TPMT genotype, which correlates with their ability to metabolize thiopurine drugs. This genetic information is crucial for optimizing drug dosages and minimizing adverse drug reactions.
Sample Required
Whole Blood (WB) in EDTA Vacutainer
(A sample of whole blood collected in an EDTA vacutainer is required for this test. EDTA acts as an anticoagulant to preserve the blood sample for DNA extraction.)
Preparation
No specific preparation is typically required for this genetic test. * No Fasting Required: Fasting is not necessary for this blood sample collection. * No Special Timing: Blood can be drawn at any ti... Read more
Schedule Report
7 Days
Emergency Report
Yes
Frequently Asked Questions
No data available
Test Description
- High-end laboratory & medical equipment.
- Outstanding doctor team.
- Personalized care & high-quality service.
- Tailormade health screening packages.