Molecular Genetic Factor II ( Prothrombin ) Mutation Analysis - RT-PCR
Test Code
MOG07
Also Known As
No data available
Test Parameters Included
No data available
Department
MOLECULAR GENETICS
Methodology
RT-PCR (Reverse Transcription Polymerase Chain Reaction) / PCR / Allele-Specific PCR
The Molecular Genetic Factor II (Prothrombin) Mutation Analysis primarily utilizes PCR (Polymerase Chain Reaction) technology, often specifically Allele-Specific PCR (AS-PCR). While the prompt mentions RT-PCR, for DNA-based point mutations, standard PCR is commonly applied directly to DNA. This highly sensitive molecular technique is designed to specifically detect the G20210A point mutation in the Factor II (prothrombin) gene. AS-PCR uses primers that are specifically designed to bind only to the mutated DNA sequence, allowing for selective amplification of the mutated allele. The amplification of a specific product indicates the presence of the G20210A mutation. This method provides highly accurate qualitative detection, determining the presence or absence of this key genetic alteration associated with an increased risk of blood clots.
Sample Required
WB EDTA Whole Blood (WB) in EDTA Vacutainer
(A sample of whole blood collected in an EDTA vacutainer is required for this test. EDTA acts as an anticoagulant to preserve the blood sample for DNA extraction.)
Preparation
No specific preparation is typically required for this genetic test. * No Fasting Required: Fasting is not necessary for this blood sample collection. * No Special Timing: Blood can be drawn at any ti... Read more
Schedule Report
3 Days
Emergency Report
Yes
Frequently Asked Questions
No data available
Test Description
- High-end laboratory & medical equipment.
- Outstanding doctor team.
- Personalized care & high-quality service.
- Tailormade health screening packages.